Pushing the Boundaries of Regenerative Science

Amniotic Derived Exosomes with Platelet Rich Fibrin Combined in the Treatment of Hip and Knee Osteoarthritis: A Retrospective 1-Year Follow-Up Study

• 114 patients with 1-year follow-up
• Exosome treatment for knees and hips
• Significantly lowered WOMAC score.
• Increased cartilage on ultrasound before- and after pictures.

Platelet Rich Fibrin Combined with Hyaluronic Acid in the Treatment of Meniscal Injuries: A Retrospective 1-Year Follow-Up Study

• 78 patients with 1-year follow-up
• Reduced pain according to NRS pain scores
• Positive effect shown through sonographic imaging
• Long-lasting effect
• PRF combined with hyaluronic acid

Hydrogel alone or in Combination with Regenerative Interventions for Knee Osteoarthritis, A Case Series

• Case series with promising results
• Reduced pain according to NRS pain scores and WOMAC
• A "membrane" effect where the hydrogel acts as a scaffold for cells was shown.

Platelet-Rich Fibrin in Combination with Heat-Coagulated Albumin Gel as Treatment for Lateral Epicondylitis: A Retrospective 1-Year Follow-Up Study

• 528 patients with 1-year follow-up
• Platelet injection combined with albumin gel
• Long-lasting effect indicated by follow-up data
• Reduced pain according to NRS pain scores

Exosome-Based Therapy for Osteoarthritis: A Systematic Review

• Systematic review
• 27 research articles
• Exosomes demonstrate strong anti-inflammatory and regenerative properties

Stromal Vascular Fraction with Platelet-Rich Fibrin for Osteoarthritis Management in Knee and Hip Osteoarthritis: A Retrospective 2-Year Follow-Up Study

• 104 patients with 2-year follow-up
• Stem cells and Platelet injections combined with heat-coagulated albumin gel
• Long-lasting effect indicated by follow-up data
• Reduced pain according to NRS pain scores
• Increased joint space on radiographic before- and after pictures.

Amniotic Derived Exosomes in the Treatment of Degenerative Bone- and Cartilage Disease: A Case Series

• Case series of 3 male patients with chronic, treatment-resistant pain
• Significant reduction in pain and improved joint function after a single exosome injection
• Suggests strong regenerative potential when combined with PRF and SVF therapies

Treatment of Osgood-Schlatter Disease in an Adolescent Athlete with Liquid Platelet-Rich Fibrin and Heat-Coagulated Albumin Gel: A Case Report

• Case report of a 13-year-old boy with 3-year chronic Osgood-Schlatter disease
• Complete remission of ossification and pain after three injections of PRF and ALB-PRF
• Returned to elite-level sports within 2 months; no relapse after 2 years

Treatment of a Fractured Humerus and Partially Torn Supraspinatus Tendon in a Professional Boxer with Liquid Platelet-Rich Fibrin and Heat-Coagulated Albumin Gel: A Case Report

• 33-year-old professional boxer with delayed humerus fracture and rotator cuff tear
• Full clinical recovery and radiographic healing achieved within 1 month using PRF and ALB-PRF
• Returned to professional boxing in 3 months, no relapse after 1 year

Regenerative Medicine Treatment Using Stromal Vascular Fraction (SVF) and Platelet-Rich Fibrin (PRF)

• Case series across 7 patients with osteoarthritis in joints including knee, hip, ankle, shoulder, hand, and foot
• All patients treated with SVF and PRF injections combined with structured rehabilitation; notable improvements in pain, mobility, and joint space on imaging
• SVF (adipose-derived stem cells) and PRF used as a minimally invasive alternative to surgery—patients returned to daily activities and sports, some after years of inactivity